International Journal of  Applied Bioresearch (IJAB)

The quarterly peer-reviewed journal
91 - 9487567793

ISSN 2250 - 2033 (Print); e -ISSN: 2250 - 2041 (Online)

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Gayathri Global Academic & Scientific Publisher (GGASP),India
Forth Coming Issue
Volume No 44(2) May- September,2025
Volume No 43 (4) December,2024
M. Maridass
FISSD’S - Research Institute of Conservation Ecology (Run by Foundation for Innovative Science and Socio-Economic Development (FISSD’S), Arunagiri Complex, Palayamkottai Tirunelveli, Tamilnadu-627002,India.
 
Email: drmaridass@gmail.com; Mobile: : +91-9487567793
 
 
Preliminary phytochemical investigations and Antibacterial activity of some Medicinal plants 
 
 
Abstract
Aim: This study evaluates the preliminary phytochemical screening and antimicrobial effects of petroleum ether extract of five selected medicinal plants of Cardiospermum halicacabum (L.) leaves, Ervatamia divaricata (L.) Burkill leaves, Curcuma zedoaria rhizome, Clerodendrum inerme ( L.) Gaertn  leaves and Sida rhombifolia L. leaves.
 
Methods: Dried plant materials of selected plants were extracted with petroleum ether in a Soxhlet apparatus for 3hr.  The collected extracts were screened for phytochemicals and studied for their antibacterial activity using the agar disc diffusion technique. 
Results: The result of the present study observed that extraction values of C.inerme (L.) Gaertn exhibit the highest yield at 6.4%, while the extract from the rhizome of C.zedoaria shows the lowest yield at 2.2%. The preliminary phytochemical investigation of petroleum ether extracts of the leaves of C.halicacabum (L.), E.divaricata (L.) Burkill, and C.inerme (L.) Gaertn as well as the rhizome of C.zedoaria and the leaves of Sida rhombifolia L., revealed that this plant tested for positive results were alkaloids, flavonoids, and terpenoids while active compounds of Tannin and saponins were absent.  The medicinal plants of Curcuma zedoaria rhizome had good antibacterial activity against S. aureus and Bacillus subtilis.
Conclusion: The petroleum ether extracts of the chosen plants were examined in this study indicate that these extracts may serve as more effective antimicrobial agents.
 
Keywords: Antimicrobial activity, plant extract, Gram positive, Gram negative