Pteridological Research : Volume No. 13(2)

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+91 - 9487567793

ISSN 2319-1910 (Print)

Fern Journal

Pteridological Research

Vol.No.13(2):1-4. (July-December,2024)

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Research Article

Antiinflammatory activity of rhizome of Drynaria quercifolia (L.) J.Sm (Polypodiaceae)

M. Maridass

FISSD’S- Research Institute of Conservation Ecology (Run by Foundation for Innovative Science and Socio Economic Development (FISSD’S), Arunagiri Complex, Palayamkottai Tirunelveli,

Tamilnadu-627002,India.

Email: drmaridass@gmail.com; Mobile : +91-9487567793

Abstract

Plant-derived phytochemicals are recognized for their potential as sources of antimicrobial and anti-inflammatory compounds. The natural compounds derived from these plants exhibited encouraging anti-inflammatory properties for the treatment of vari-ous inflammatory conditions affecting the skin, liver, cardiovascular system, joints, gastrointestinal tract, nervous system, and lungs. Pteridophytes, commonly referred to as ferns and their relatives, possess antimicrobial characteristics that can be utilized in the treatment of bacterial and fungal infections. Aim of the present study was investigation of anti-inflammatory properties of rhizome of Drynaria quercifolia (L.) J.Sm.

Methods: Powdered materials of D.quercifolia rhizome were extracted with ethanol for 3h and collected the extract and their extract studied for carrageenan-induced paw edema model in Wistar rats. Ethanolic extract of D. quercifolia rhizome and stand-ard drug of Diclofenac sodium (10 mg/kg) compared to carrageenan control at different hours in carrageenan-induced paw ede-ma model in Wistar rats.

Results: Ethanolic extract of D.quercifolia rhizome was administered at a dose of 500 mg/kg p.o prevented carrageenan-induced paw edema with a percentage inhibition at 66.91% in 3h. Ethanolic extracts of D. quercifolia tested doses of 100, 200 and 500 mg/kg had been a significant reduction in carrageenan-induced paw edema in rats, with inhibition rates of 30.01%, 54.21%, and 65.66 % respectively. The findings of the current study indicate that the rhizome of D. quercifolia exhibits signifi-cant anti-inflammatory properties. Active compounds were identified in the extracts derived from the rhizome of D.quercifolia , which demonstrated anti-inflammatory effects that were dependent on concentration. Consequently, it is recommended that fur-ther purification and assessment of these extracts, along with a more detailed investigation into the anti-inflammatory potential of the plant, be conducted.