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Anti-inflammatory activity of some medicinal plants in India
Muthiah MARIDASS and Ganapathy RAJU
Department of Zoology, Pioneer Kumaraswamy College, (Affiliated to Manonmaniam Sundaranar University), Nagercoil,Tamil nadu-629003, India.
Curresponding Author Email: maridassugcpdf@yahoo.co.in
Abstract
In the present study, investigation of phytochemical constituents of Cymbopogon citratus (DC.) Stapf. Hemidesmus indicus (L.) R. Br. (Periplocaceae), Sonerila tinnevelliensis Fischer, Goniothalamus wightii J. Hk. & Thoms. and Psychotria nudiflora Wight & Arn. and anti-inflammatory activity of carrageenan-induced rat paw edema models. The results of active compounds were identified in alkaloids, flavonoids, sterols and essential oils were found to be all plants extracts. The pharmacological activity of anti-inflammatory activity was studied in carragennan induced rat paw edema model observed by 6 hrs. The results were demonstrated that the higher percentage of inhibition of petroleum ether extract of selected plants viz. S. tinnevelliensis (88.46%), P. nudiflora (87.98%), C. citratus (86.12%), G. wightii (77.96%) and H. indicus (77.89%) respectively and compared to control and standard ibuprofen, which is statistically significant.
Keywords: Phytochemicals, inflammatory activity, medicinal plants, medicine